Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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151
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151
Tocris Bioscience™ SLM 6031434 hydrochloride
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Selective sphingosine kinase 2 (Sphk2) inhibitor
| CAS | 1897379-34-8 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | (2S)-2-[3-[4-(Octyloxy)-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]-1-pyrrolidinecarboximidamide hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H30F3N5O2.HCl |
152
Tocris Bioscience™ CG 858
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Selective BRAF-V600E protein Degrader (uSMITE™)
153
Tocris Bioscience™ SW 033291
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High affinity 15-PGDH inhibitor; promotes hematopoiesis and hepatocyte proliferation
| Target | Dehydrogenase Inhibitors |
|---|---|
| CAS | 459147-39-8 |
| Purity | >98% |
| Chemical Name or Material | 2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H20N2OS3 |
| Formula Weight | 412.59 |
154
Tocris Bioscience™ dBET6
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Potent and selective (+)-JQ1 based Degrader (PROTAC™) targeting BET bromodomains, active in vivo
156
Tocris Bioscience™ GYKI 52466 dihydrochloride
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CAS: 2319722-40-0 Molecular Formula: C17H15N3O2
| CAS | 2319722-40-0 |
|---|---|
| Molecular Formula | C17H15N3O2 |
157
Tocris Bioscience™ AF-DX 384
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CAS: 118290-26-9 Molecular Formula: C27H38N6O2
| CAS | 118290-26-9 |
|---|---|
| Molecular Formula | C27H38N6O2 |
158
Tocris Bioscience™ SynaptoRed C2
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Fluorescent dye; stains synaptic vesicles
159
Tocris Bioscience™ PD 146176
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 4079-26-9 Molecular Formula: C15H11NS
| CAS | 4079-26-9 |
|---|---|
| Molecular Formula | C15H11NS |
160
Tocris Bioscience™ (R)-(-)-Rolipram
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 85416-75-7 Molecular Formula: C16H21NO3
| CAS | 85416-75-7 |
|---|---|
| Molecular Formula | C16H21NO3 |
161
Tocris Bioscience™ Melatonin
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CAS: 73-31-4 Molecular Formula: C13H16N2O2
| CAS | 73-31-4 |
|---|---|
| Molecular Formula | C13H16N2O2 |
162
Tocris Bioscience™ NR12S
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Fluorogenic lipid membrane dye
163
| CAS | 161814-49-9 |
|---|---|
| Molecular Formula | C25H35N3O6S |
164
Tocris Bioscience™ TCS JNK 6o
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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TCS JNK 6o synthesized to Ancillary Material Grade
165
Tocris Bioscience™ Thalidomide 4'-oxyacetamide-PEG3-amine
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PROTACs (Proteolysis Targeting Chimeras)